Trade Associations
Here's a look at documents from national and international trade associations
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Young Adults With Elevated Cholesterol Often Go Untreated, Study Finds
WASHINGTON, Nov. 11 -- The American College of Cardiology posted the following news release:
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Young Adults With Elevated Cholesterol Often Go Untreated, Study Finds
Research highlights declining statin use and follow-up testing in high-risk 18-39-year-olds
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Fewer than half of young adults with severely high low-density lipoprotein (LDL-C), or "bad" cholesterol, levels start taking a statin within five years of first high LDL-C measurement, according to a study published in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association's
... Show Full Article
WASHINGTON, Nov. 11 -- The American College of Cardiology posted the following news release:
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Young Adults With Elevated Cholesterol Often Go Untreated, Study Finds
Research highlights declining statin use and follow-up testing in high-risk 18-39-year-olds
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Fewer than half of young adults with severely high low-density lipoprotein (LDL-C), or "bad" cholesterol, levels start taking a statin within five years of first high LDL-C measurement, according to a study published in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association's2025 Scientific Sessions. The 2018 ACC/AHA Cholesterol Guideline recommends a statin in patients with LDL-C over 190 mg/dL and these findings highlight significant care gaps in lipid management among adults aged 18 to 39, particularly those at high risk for premature atherosclerotic cardiovascular disease (ASCVD).
People with elevated LDL-C are more likely to have a heart attack or stroke. More than half of U.S. young adults have elevated LDL-C levels (above 100 mg/dL), yet they are significantly less likely than older adults to be aware of their cholesterol levels or receive recommended treatment. This study is one of the largest to date examining real-world patterns of LDL-C testing and statin initiation in this age group.
"Within our integrated system in Southern California, we observed that some high -risk young adults were not consistently following up with the LDL-C testing or statin therapy recommended by guidelines." said Teresa N. Harrison, SM, a researcher at Kaiser Permanente Southern California Department of Research & Evaluation and lead author of the study. "Our findings underscore that early adulthood is a critical window for prevention, and identifying these areas of opportunities for earlier intervention is essential to reducing young adults' lifelong heart risk."
Researchers analyzed data from 771,681 members of Kaiser Permanente Southern California aged 18-39 years who had their first elevated LDL-C measurement between 2008 and 2020. Participants were stratified by LDL-C levels and groups at high-risk of ASCVD, and researchers tracked follow-up LDL-C testing and statin initiation over one, two, and five years.
Key findings include:
* Among those with LDL-C 190 mg/dL, only 28.4% initiated a statin within one year, and only 45.7% by five years.
* Among those with LDL-C 160-189 mg/dL and high 30-year ASCVD risk, 25.3% initiated a statin within one year, rising to 46.4% within five years.
* Follow-up LDL-C testing within one year declined from 52.5% in 2008 to 35.4% in 2018 among high-risk individuals.
* Statin initiation within one year also declined from 31.7% to 20.1% for those with LDL-C 160-189 mg/dL and high risk, and from 36.5% to 12.6% for those with LDL-C 190 mg/dL.
"The good news is that health care systems have a potential roadmap to develop next-generation care models," Harrison said. "The promising results from our safety net program, SureNet, suggest that integrating patient outreach and clinician decision support may be an effective strategy to further advance proactive, early cardiovascular prevention."
Harlan M. Krumholz, MD, SM, Editor-in-Chief of JACC, said the findings highlight how often opportunities for prevention are being missed, and for many young adults, elevated LDL cholesterol marks the start of a decades-long exposure to cardiovascular risk.
"By identifying and addressing these gaps early, we can change the trajectory of heart disease across the lifespan," Krumholz said.
This study was conducted within a large, insured health system population in Southern California, which may limit how broadly the findings apply to uninsured populations or those in different care settings. The researchers did not assess whether patients consistently took their prescribed statins, which could influence long-term cardiovascular outcomes. Additionally, the study did not capture patient or clinician perspectives on why statins weren't started or follow-up testing wasn't complete --factors that may play a key role in real-world treatment decisions.
The findings will be presented at AHA.25 on Monday, November 10, at 1:00 p.m. CT / 2:00 p.m. ET. For an embargoed copy of the study "Follow-up Lipid Testing and Statin Initiation among Young Adults in a US Healthcare System," contact JACC Media Relations Manager Olivia Walther at owalther@acc.org.
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The American College of Cardiology (ACC) is a global leader dedicated to transforming cardiovascular care and improving heart health for all. For more than 75 years, the ACC has empowered a community of over 60,000 cardiovascular professionals across more than 140 countries with cutting-edge education and advocacy, rigorous professional credentials, and trusted clinical guidance. From its world-class JACC Journals and NCDR registries to its Accreditation Services, global network of Chapters and Sections, and CardioSmart patient initiatives, the College is committed to creating a world where science, knowledge and innovation optimize patient care and outcomes. Learn more at www.ACC.org or connect on social media at @ACCinTouch.
The ACC's JACC Journals rank among the top cardiovascular journals in the world for scientific impact. The flagship journal, the Journal of the American College of Cardiology (JACC) -- and specialty journals consisting of JACC: Advances, JACC: Asia, JACC: Basic to Translational Science, JACC: CardioOncology, JACC: Cardiovascular Imaging, JACC: Cardiovascular Interventions, JACC: Case Reports, JACC: Clinical Electrophysiology and JACC: Heart Failure -- pride themselves on publishing the top peer-reviewed research on all aspects of cardiovascular disease. Learn more at JACC.org.
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Original text here: https://www.acc.org/About-ACC/Press-Releases/2025/11/10/19/29/Young-Adults-With-Elevated-Cholesterol-Often-Go-Untreated-Study-Finds
[Category: Medical]
National MS Society: Results Announced - "BTK Inhibitor" Fenebrutinib Meets Primary Endpoint in Phase 3 Trials in People With Primary Progressive and Relapsing MS
NEW YORK, Nov. 11 -- The National Multiple Sclerosis Society issued the following news:
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Results Announced: "BTK Inhibitor" Fenebrutinib Meets Primary Endpoint in Phase 3 Trials in People with Primary Progressive and Relapsing MS
Genentech, a member of the Roche Group, announced that fenebrutinib - an experimental, oral BTK-inhibitor - met the primary endpoint of slowing disability progression at least as effectively as ocrelizumab in the FENtrepid study in people with primary progressive MS. Fenebrutinib also met the primary endpoint of significantly reducing relapses compared to teriflunomide
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NEW YORK, Nov. 11 -- The National Multiple Sclerosis Society issued the following news:
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Results Announced: "BTK Inhibitor" Fenebrutinib Meets Primary Endpoint in Phase 3 Trials in People with Primary Progressive and Relapsing MS
Genentech, a member of the Roche Group, announced that fenebrutinib - an experimental, oral BTK-inhibitor - met the primary endpoint of slowing disability progression at least as effectively as ocrelizumab in the FENtrepid study in people with primary progressive MS. Fenebrutinib also met the primary endpoint of significantly reducing relapses compared to teriflunomidein the FENhance 2 study in people with relapsing MS.
These results were announced in a press release on November 10. Detailed results will be presented at upcoming medical meetings.
Background: Fenebrutinib inhibits an enzyme called "Bruton's tyrosine kinase," reducing the activation of B cells, which are immune cells that play a role in the response that affects the brain and spinal cord in MS. Fenebrutinib also inhibits immune cells in the brain called microglia, which have been linked to MS progression. Fenebrutinib is one of several "BTK" inhibitors being tested in clinical trials involving people with different types of MS. One BTK inhibitor, tolebrutinib, is under review at the U.S. Food & Drug Administration.
Details:
* The primary outcome of the FENtrepid study compared how fentrepid and ocrelizumab affected disability progression in 985 people with primary progressive MS, using a composite measure that combines the EDSS scale of disability progression with measures of walking and hand function. The results show that fenebrutinib delayed progression as well as ocrelizumab over at least 120 weeks; a benefit for fenebrutinib was observed from week 24 onward.
* The primary outcome of the FENhance 2 study compared how fenebrutinib and teriflunomide affected the annual rate of relapses in 751 people with relapsing MS. Relapsing MS includes relapsing-remitting disease and active secondary progressive disease (with relapses). Fenebrutinib significantly reduced the annual rate of relapses compared to teriflunomide over at least 96 weeks of treatment.
* Preliminary assessment of liver safety was consistent with previous studies, according to the press release.
The press release notes that data will be considered for submission to regulatory authorities after results are available for a second phase 3 study in 746 people with relapsing MS (FENhance 1), which is expected to occur in the first half of 2026.
Learn more...
Learn more about Treating MS
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About Multiple Sclerosis
Multiple sclerosis is an unpredictable disease of the central nervous system. Currently there is no cure. Symptoms vary from person to person and may include disabling fatigue, mobility challenges, cognitive changes, and vision issues. An estimated 1 million people live with MS in the United States. Early diagnosis and treatment are critical to minimize disability. Significant progress is being made to achieve a world free of MS.
About the National Multiple Sclerosis Society
The National MS Society, founded in 1946, is the global leader of a growing movement dedicated to creating a world free of MS. The Society funds cutting-edge research for a cure, drives change through advocacy and provides programs and services to help people affected by MS live their best lives. Connect to learn more and get involved: nationalmssociety.org, Facebook, X (formerly known as Twitter), Instagram, YouTube or 1-800-344-4867.
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Original text here: https://www.nationalmssociety.org/news-and-magazine/news/research-breaking-news-2
[Category: Health Care]
CNBC/NRF Retail Monitor's October Data Shows 'Continued Momentum' Going Into Holiday Season
WASHINGTON, Nov. 11 -- The National Retail Federation posted the following news release on Nov. 10, 2025:
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CNBC/NRF Retail Monitor's October Data Shows 'Continued Momentum' Going Into Holiday Season
Retail sales bounced back in October, showing both monthly and year-over-year gains heading into the holiday shopping season, according to the CNBC/NRF Retail Monitor, powered by Affinity Solutions, released today by the National Retail Federation.
"Retail sales grew in October as consumers geared up for the holiday season," NRF President and CEO Matthew Shay said. "Recent economic data has
... Show Full Article
WASHINGTON, Nov. 11 -- The National Retail Federation posted the following news release on Nov. 10, 2025:
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CNBC/NRF Retail Monitor's October Data Shows 'Continued Momentum' Going Into Holiday Season
Retail sales bounced back in October, showing both monthly and year-over-year gains heading into the holiday shopping season, according to the CNBC/NRF Retail Monitor, powered by Affinity Solutions, released today by the National Retail Federation.
"Retail sales grew in October as consumers geared up for the holiday season," NRF President and CEO Matthew Shay said. "Recent economic data hasbeen mixed, yet consumer spending remains solid -- supported by wage growth outpacing inflation, historically low unemployment, and wealth effects from strong stock market valuations. These factors point to continued momentum heading into the holidays as consumers focus on family, friends and finding value to make their budgets go further."
Total retail sales, excluding automobile dealers and gasoline stations, were up 0.6% seasonally adjusted month over month and up 5% unadjusted year over year in October, according to the Retail Monitor. That compared with a decrease of 0.66% month over month and an increase of 5.42% year over year in September.
The Retail Monitor calculation of core retail sales (excluding restaurants in addition to automobile dealers and gasoline stations) was also up 0.6% month over month in October and up 4.89% year over year. That compared with a decrease of 0.49% month over month and an increase of 5.72% year over year in September.
Total sales were up 5.11% year over year for the first 10 months of the year and core sales were up 5.28%.
The October results come as NRF is forecasting that 2025 holiday sales will increase between 3.7% and 4.2% compared with 2024 to just over $1 trillion.
Chart: CNBC/NRF Retail Monitor
Unlike survey-based numbers collected by the Census Bureau, the Retail Monitor uses actual, anonymized credit and debit card purchase data compiled by Affinity Solutions and does not need to be revised monthly or annually.
October sales were up in all but two of nine categories on a yearly basis, led by digital products, clothing store and sporting goods stores, and were also up in all but two categories on a monthly basis. Specifics from key sectors include:
* Digital products (such as electronic books and games) were up 2.02% month over month seasonally adjusted and up 22.39% year over year unadjusted.
* Clothing and accessories stores were up 1.42% month over month seasonally adjusted and up 7.89% year over year unadjusted.
* Sporting goods, hobby, music and book stores were up 0.09% month over month seasonally adjusted and up 7.19% year over year unadjusted.
* General merchandise stores were up 0.58% month over month seasonally adjusted and up 6.99% year over year unadjusted.
* Electronics and appliance stores were up 0.13% month over month seasonally adjusted and up 6.58% year over year unadjusted.
* Grocery and beverage stores were up 0.59% month over month seasonally adjusted and up 4.08% year over year unadjusted.
* Health and personal care stores were up 0.58% month over month seasonally adjusted and up 1.9% year over year unadjusted.
* Furniture and home furnishings stores were down 0.08% month over month seasonally adjusted and down 1.7% year over year unadjusted.
* Building and garden supply stores were down 0.81% month over month seasonally adjusted and down 8.52% year over year unadjusted.
To learn more, visit nrf.com/nrf/cnbc-retail-monitor.
As the leading authority and voice for the retail industry, NRF provides data on retail sales each month and also forecasts annual retail sales and spending for key periods such as the holiday season each year.
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About NRF
The National Retail Federation passionately advocates for the people, brands, policies and ideas that help retail succeed. From its headquarters in Washington, D.C., NRF empowers the industry that powers the economy. Retail is the nation's largest private-sector employer, contributing $5.3 trillion to annual GDP and supporting more than one in four U.S. jobs -- 55 million working Americans. For over a century, NRF has been a voice for every retailer and every retail job, educating, inspiring and communicating the powerful impact retail has on local communities and global economies. nrf.com
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Original text here: https://nrf.com/media-center/press-releases/cnbc-nrf-retail-monitor-s-october-data-shows-strong-momentum-going-into-holiday-season
[Category: Business]
BSA Encourages Restoration of Cybersecurity Info-Sharing
WASHINGTON, Nov. 11 -- Business Software Alliance (formerly BSA - Software Alliance) issued the following statement on Nov. 10, 2025:
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BSA Encourages Restoration of Cybersecurity Info-Sharing
BSA Senior Director of Policy Henry Young released the following statement on reports that CISA 2015 will be restored in the tentative deal to reopen the government:
"The Business Software Alliance is encouraged by reports that the tentative deal to reopen the government includes the restoration of CISA 2015, a critical authority that helps protect all Americans. Congress should build upon this welcome
... Show Full Article
WASHINGTON, Nov. 11 -- Business Software Alliance (formerly BSA - Software Alliance) issued the following statement on Nov. 10, 2025:
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BSA Encourages Restoration of Cybersecurity Info-Sharing
BSA Senior Director of Policy Henry Young released the following statement on reports that CISA 2015 will be restored in the tentative deal to reopen the government:
"The Business Software Alliance is encouraged by reports that the tentative deal to reopen the government includes the restoration of CISA 2015, a critical authority that helps protect all Americans. Congress should build upon this welcomestep by reauthorizing this bipartisan law, which strengthens cybersecurity by removing barriers to information sharing."
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ABOUT BSA
The Business Software Alliance (www.bsa.org) is the global trade association of the enterprise software industry, representing companies that are leaders in artificial intelligence, cybersecurity, cloud computing, quantum, and other breakthrough technologies. We work in over 20 markets in the US, Europe, and Asia, advocating for policies that build trust in technology so that every industry sector and the public can benefit from innovation.
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Original text here: https://www.bsa.org/news-events/news/bsa-encourages-restoration-of-cybersecurity-info-sharing
[Category: Business]
American College of Surgeons Releases New Best Practices Guidelines for Managing Chest Wall Injuries
CHICAGO, Illinois, Nov. 11 -- The American College of Surgeons issued the following news release:
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American College of Surgeons Releases New Best Practices Guidelines for Managing Chest Wall Injuries
Updated guidelines provide evidence-based recommendations for treating traumatic rib and breastbone fractures, with a focus on stabilizing patients and providing effective pain management
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The American College of Surgeons (ACS) has released new Best Practices Guidelines for the Management of Chest Wall Injuries, providing health care professionals with comprehensive, evidence-based strategies
... Show Full Article
CHICAGO, Illinois, Nov. 11 -- The American College of Surgeons issued the following news release:
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American College of Surgeons Releases New Best Practices Guidelines for Managing Chest Wall Injuries
Updated guidelines provide evidence-based recommendations for treating traumatic rib and breastbone fractures, with a focus on stabilizing patients and providing effective pain management
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The American College of Surgeons (ACS) has released new Best Practices Guidelines for the Management of Chest Wall Injuries, providing health care professionals with comprehensive, evidence-based strategiesto improve care for patients with rib and significant sternal (breastbone) fractures.
Chest wall injuries, particularly rib fractures, are among the most common injuries in trauma patients and are a major contributor to trauma-related deaths. These injuries can lead to severe pain, impaired breathing, pneumonia, and longer hospital stays, with mortality rates as high as 36% in patients with flail chest. Flail chest occurs when multiple ribs are broken in multiple places, interfering with the body's ability to breathe normally. The new guidelines address the full spectrum of care, from initial assessment and nonoperative management to indications and techniques to ensure patients are stable after trauma.
"Management of chest wall injuries has evolved dramatically, moving beyond the old paradigm of 'they will heal on their own' to a proactive, multidisciplinary approach that can significantly improve patient outcomes," said Avery Nathens, MD, PhD, FACS, Medical Director of Trauma Quality Programs at the ACS. "These guidelines represent the latest evidence to help trauma teams effectively manage pain, prevent complications, and determine when surgical intervention is the best course of action."
Key points from the guidelines
* Surgical Stabilization of Rib Fractures (SSRF): In patients with flail chest and respiratory failure, there is a strong recommendation for stabilizing the fractured ribs using metal plates or other surgical hardware. Guidance is also provided on relative indications for SSRF in patients with multiple displaced fractures without flail chest.
* Multimodal Pain Management: The guidelines place an emphasis on pain management techniques that do not rely on opioids, including regional anesthesia techniques like epidural analgesia, paravertebral blocks, and serratus anterior plane blocks.
* Optimal Timing for Surgery: While not always possible, SSRF is recommended within 48-72 hours of injury to reduce ventilator time, ICU and hospital length of stay, and complications such as pneumonia.
* Special Populations: Tailored recommendations for older adult trauma patients and patients who have sustained multiple traumatic injuries, including those with traumatic brain injury or pulmonary contusion.
* Postoperative and Rehabilitation Care: Best practices for managing pleural space (the space around the lungs), monitoring pulmonary function, and the critical role of patients being mobile after surgery and aggressive pulmonary hygiene through a comprehensive set of measures aimed at maintaining optimal lung health and preventing respiratory complications
The guidelines were developed by a multidisciplinary panel of experts, including trauma surgeons, orthopaedic surgeons, thoracic surgeons, anesthesiologists, and allied health professionals with the publication endorsed by the Chest Wall Injury Society (CWIS) and the Orthopaedic Trauma Association (OTA).
"These guidelines provide crucial insights into the operative and nonoperative management of these painful injuries, including older patients who are particularly vulnerable to complications," said Dr. Nathens. "This comprehensive resource will help standardize care and ensure all patients receive the highest quality care."
The Best Practices Guidelines for the Management of Chest Wall Injuries are now available on the ACS website.
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About the American College of Surgeons
The American College of Surgeons is a scientific and educational organization of surgeons that was founded in 1913 to raise the standards of surgical practice and improve the quality of care for all surgical patients. The College is dedicated to the ethical and competent practice of surgery. Its achievements have significantly influenced the course of scientific surgery in America and have established it as an important advocate for all surgical patients. The College has approximately 90,000 members and is the largest organization of surgeons in the world. "FACS" designates that a surgeon is a Fellow of the American College of Surgeons.
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Original text here: https://www.facs.org/media-center/press-releases/2025/american-college-of-surgeons-releases-new-best-practices-guidelines-for-managing-chest-wall-injuries/
[Category: Medical]
Airlines for America Statement on Senate Vote to Reopen Government
WASHINGTON, Nov. 11 -- Airlines for America issued the following news:
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Airlines for America Statement on Senate Vote to Reopen Government
The following statement is attributable to Airlines for America (A4A):
We commend the Senate for coming together with a bipartisan deal and doing their part to reopen the government. We especially appreciate the senators who recognized the unsustainable difficulties and challenges being inflicted on Americans--including significant disruptions for the traveling and shipping public.
Airlines' reduced flight schedules cannot immediately bounce back to
... Show Full Article
WASHINGTON, Nov. 11 -- Airlines for America issued the following news:
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Airlines for America Statement on Senate Vote to Reopen Government
The following statement is attributable to Airlines for America (A4A):
We commend the Senate for coming together with a bipartisan deal and doing their part to reopen the government. We especially appreciate the senators who recognized the unsustainable difficulties and challenges being inflicted on Americans--including significant disruptions for the traveling and shipping public.
Airlines' reduced flight schedules cannot immediately bounce back tofull capacity right after the government reopens. It will take time, and there will be residual effects for days. With the Thanksgiving travel period beginning next week and the busy shipping season around the corner, the time to act is now to help mitigate any further impacts to Americans.
We encourage the House to pass the bill swiftly.
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Original text here: https://www.airlines.org/news-update/airlines-for-america-statement-on-senate-vote-to-reopen-government/
[Category: Transportation]
Airlines for America Statement on Senate Cloture Vote
WASHINGTON, Nov. 11 -- Airlines for America issued the following news:
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Airlines for America Statement on Senate Cloture Vote
The following statement is attributable to Airlines for America (A4A):
On behalf of every American traveler and shipper, Airlines for America is grateful that the Senate is considering a bipartisan agreement to reopen the federal government and pay the essential air traffic controllers, TSA and CBP officers for the essential work they do every day. At a time of record air travel and increased reliance on cargo shipments, it is more important than ever to ensure
... Show Full Article
WASHINGTON, Nov. 11 -- Airlines for America issued the following news:
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Airlines for America Statement on Senate Cloture Vote
The following statement is attributable to Airlines for America (A4A):
On behalf of every American traveler and shipper, Airlines for America is grateful that the Senate is considering a bipartisan agreement to reopen the federal government and pay the essential air traffic controllers, TSA and CBP officers for the essential work they do every day. At a time of record air travel and increased reliance on cargo shipments, it is more important than ever to ensurethat our nation's airspace is safe, reliable and open. Now that the continuing resolution (CR)/minibus package has been offered, we strongly encourage the Senate to pass it swiftly and send it to the House with urgency.
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Original text here: https://www.airlines.org/news-update/airlines-for-america-statement-on-senate-cloture-vote/
[Category: Transportation]
