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Northwestern University: Shape of Water Defines the Hotspot That Starts Protein Aggregation in Dementia
October 12, 2026
EVANSTON, Illinois, Oct. 12 (TNSjou) -- Northwestern University posted the following news release:

* * *

The shape of water defines the hotspot that starts protein aggregation in dementia

Blocking that single spot stopped misfolded tau proteins from spreading and points to a new drug target

October 12, 2026

* Tau proteins misfold and stack into long fibrils that disrupt neurons, and when released, can cause tau in neighboring cells . . .

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