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Removing immune 'brake' improves CAR T-cell therapy for osteosarcoma
August 25, 2026
MEMPHIS, Tennessee, Aug. 25 [Category: BizHospital] -- St. Jude Children's Research Hospital issued the following news release:

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Removing immune 'brake' improves CAR T-cell therapy for osteosarcoma

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Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma. There is great clinical need . . .

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