Turning the tables on chemotherapy resistance: LIG1 loss exposes a therapeutic vulnerability in triple-negative breast cancer
July 16, 2026
July 16, 2026
HOUSTON, Texas, July 16 -- The Baylor College of Medicine posted the following news:
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Turning the tables on chemotherapy resistance: LIG1 loss exposes a therapeutic vulnerability in triple-negative breast cancer
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Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions have i . . .
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Turning the tables on chemotherapy resistance: LIG1 loss exposes a therapeutic vulnerability in triple-negative breast cancer
*
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions have i . . .