Disrupting genome architecture selectively impairs developmental genes
April 13, 2026
April 13, 2026
ITHACA, New York, April 13 -- Cornell University posted the following news:
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Disrupting genome architecture selectively impairs developmental genes
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Temporarily disabling a protein complex that organizes DNA into loops inside the cell's nucleus drastically disrupted the three-dimensional structure of the genome, but surprisingly most genes continued to function as usual, Weill Cornell Medicine researchers found.
However . . .
* * *
Disrupting genome architecture selectively impairs developmental genes
*
Temporarily disabling a protein complex that organizes DNA into loops inside the cell's nucleus drastically disrupted the three-dimensional structure of the genome, but surprisingly most genes continued to function as usual, Weill Cornell Medicine researchers found.
However . . .