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Saint Louis University Researchers Urge Switch to Second-Generation Antihistamines
February 24, 2026
WASHINGTON, Feb. 24 -- Saint Louis University researchers found that first-generation antihistamines cause adverse effects in elderly patients and are encouraging healthcare providers to transition to safer second-generation alternatives. The study focused on patients over 65 years old who received older medications like diphenhydramine in academic emergency departments.

Cindy Bitter, associate professor of surgery at the Saint Louis University School of Medicine, indicated that whi . . .

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