Researchers Uncover How Tumors Become Resistant to Promising p53-Targeted Therapy
January 12, 2026
January 12, 2026
BOSTON, Massachusetts, Jan. 12 [Category: BizHospital] -- Mass General Brigham issued the following news release:
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Researchers Uncover How Tumors Become Resistant to Promising p53-Targeted Therapy
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Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it creates a small crevice in the mutant protei . . .
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Researchers Uncover How Tumors Become Resistant to Promising p53-Targeted Therapy
*
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it creates a small crevice in the mutant protei . . .