UC-San Diego: Visualizing a Key Step in How an NRPS Enzyme Produces an Antibiotic
January 07, 2025
January 07, 2025
LA JOLLA, California, Jan. 7 (TNSres) -- The University of California San Diego campus issued the following news:
Nonribosomal peptide synthetase (NRPS) enzymes are essential in creating important medications, such as penicillin and cyclosporine. This is done through a multi-step process where the enzymes activate amino acid building blocks and convert them into elongated peptides. Because of their large size, complex design and changing shapes, NRPS enzymes are highly dynamic and d . . .
Nonribosomal peptide synthetase (NRPS) enzymes are essential in creating important medications, such as penicillin and cyclosporine. This is done through a multi-step process where the enzymes activate amino acid building blocks and convert them into elongated peptides. Because of their large size, complex design and changing shapes, NRPS enzymes are highly dynamic and d . . .