U-M, multinational team of scientists reveal structural link for initiation of protein synthesis in bacteria
November 28, 2024
November 28, 2024
ANN ARBOR, Michigan, Nov. 28 -- The University of Michigan issued the following news:
This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry channel of the small ribosomal subunit (left, yellow). Alternatively, and likely dominant in bacteria, RNAP (green) can interact with ribosomal protein bS1 (right, cyan). bS1 binds and guides the mRNA . . .
This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry channel of the small ribosomal subunit (left, yellow). Alternatively, and likely dominant in bacteria, RNAP (green) can interact with ribosomal protein bS1 (right, cyan). bS1 binds and guides the mRNA . . .