Conformational Dynamics and Allostery Elucidate How GPCR Couple to Multiple G-Proteins, Offering Mechanistic Insights Into Coupling-Promiscuity and Novel Drug Discovery Strategies
August 03, 2024
August 03, 2024
TOKYO, Japan, Aug. 3 (TNSres) -- Tokyo Institute of Technology issued the following news release:
In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR). A2AR is a member of major dru . . .
In a groundbreaking study, a multinational research team led by Dr. Adnan Sljoka (RIKEN) and Prof. Akio Kitao (Tokyo Tech), in collaboration with Prof. Scott Prosser (University of Toronto), has carried out experimental and computational studies to elucidate the mechanisms behind G protein selectivity and efficacy in the human adenosine A2A receptor (A2AR). A2AR is a member of major dru . . .