Vanderbilt University Medical Center: A Critical Skin Enzyme
May 19, 2023
May 19, 2023
NASHVILLE, Tennessee, May 19 (TNSjou) -- Vanderbilt University Medical Center issued the following news:
Gene mutations that inactivate the enzyme PNPLA1 cause congenital ichthyosis, a rare inherited skin disease characterized by scaly and inflamed skin. Altered PNPLA1 activity also is implicated in allergic dermatitis and other common skin diseases.
Jason Meyer, MD, PhD, and colleagues studied the enzymatic properties of PNPLA1 to explore the hypothesis that it catalyz . . .
Gene mutations that inactivate the enzyme PNPLA1 cause congenital ichthyosis, a rare inherited skin disease characterized by scaly and inflamed skin. Altered PNPLA1 activity also is implicated in allergic dermatitis and other common skin diseases.
Jason Meyer, MD, PhD, and colleagues studied the enzymatic properties of PNPLA1 to explore the hypothesis that it catalyz . . .