Baylor College of Medicine: Novel Approach Prevents Liver Damage in Animal Models of Alagille Syndrome
April 08, 2023
April 08, 2023
HOUSTON, Texas, April 8 (TNSjou) -- The Baylor College of Medicine issued the following news:
Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where it often results in cholestasis, a condition in which the flow of bile from the liver stops or slows, leading to bile buildup that in time causes liver damage. Current treatments focus on delay . . .
Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where it often results in cholestasis, a condition in which the flow of bile from the liver stops or slows, leading to bile buildup that in time causes liver damage. Current treatments focus on delay . . .