Vanderbilt University Medical Center: Anti-Nausea Drug Response In Children
January 11, 2023
January 11, 2023
NASHVILLE, Tennessee, Jan. 11 (TNSjou) -- Vanderbilt University Medical Center issued the following news:
Ondansetron is commonly used in children and adults to prevent postoperative nausea and vomiting (PONV). Variation in the gene for the metabolic enzyme CYP2D6 can affect response to ondansetron, and it is recommended that alternative anti-emetic therapy be considered for adults who are ultrarapid metabolizers. However, data from pediatric populations are limited.
Sa . . .
Ondansetron is commonly used in children and adults to prevent postoperative nausea and vomiting (PONV). Variation in the gene for the metabolic enzyme CYP2D6 can affect response to ondansetron, and it is recommended that alternative anti-emetic therapy be considered for adults who are ultrarapid metabolizers. However, data from pediatric populations are limited.
Sa . . .