Vanderbilt University Medical Center: Alzheimer's Risk Factor And Cognition
November 09, 2022
November 09, 2022
NASHVILLE, Tennessee, Nov. 9 (TNSjou) -- Vanderbilt University Medical Center issued the following news:
A genetic variant of apolipoprotein E (APOE), a protein involved in fat metabolism, is the strongest common genetic risk factor for Alzheimer's disease (AD) and contributes to worse cognition in older adults. However, many people who have the variant (APOE-e4) remain cognitively normal as they age, suggesting there may be neuroprotective modifiers of APOE effects.
A genetic variant of apolipoprotein E (APOE), a protein involved in fat metabolism, is the strongest common genetic risk factor for Alzheimer's disease (AD) and contributes to worse cognition in older adults. However, many people who have the variant (APOE-e4) remain cognitively normal as they age, suggesting there may be neuroprotective modifiers of APOE effects.