Thursday - May 22, 2025
Public Policy Tipoffs Involving Pennsylvania Newsletter for Monday April 28, 2025 ( 10 items )  

A Topical BRAF-inhibiting Gel May Mitigate Acneiform Rash in Patients Receiving EGFR-targeted Therapy for Colorectal Cancer
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * A Topical BRAF-inhibiting Gel May Mitigate Acneiform Rash in Patients Receiving EGFR-targeted Therapy for Colorectal Cancer CHICAGO - Patients with colorectal cancer who had acneiform rash and applied LUT014 gel, an investigational topical BRAF inhibitor, were more likely to experience improvement of their rash compared with patients who used a plac  more

AACR Launches Its Largest-ever Grant Program to Support Early-stage and Mid-career Cancer Researchers
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * AACR Launches Its Largest-ever Grant Program to Support Early-stage and Mid-career Cancer Researchers The AACR Trailblazer Cancer Research Grant Program will award $15 million over three years CHICAGO - The American Association for Cancer Research (AACR) today announced the launch of the AACR Trailblazer Cancer Research Grant Program during the Op  more

Adding Perioperative Pembrolizumab to Standard of Care Improves Outcomes in Patients With Newly Diagnosed Head and Neck Cancer
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * Adding Perioperative Pembrolizumab to Standard of Care Improves Outcomes in Patients With Newly Diagnosed Head and Neck Cancer CHICAGO - Pembrolizumab (Keytruda) given before and after surgery to supplement adjuvant therapy improved responses and survival in patients with previously untreated, locally advanced head and neck squamous cell carcinoma (  more

Adjuvant PD-1 Blockade for Mismatch Repair-deficient Solid Cancers Directed by ctDNA Status Delivers Clinical Benefit
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * Adjuvant PD-1 Blockade for Mismatch Repair-deficient Solid Cancers Directed by ctDNA Status Delivers Clinical Benefit CHICAGO - Pembrolizumab (Keytruda), an anti-PD-1 antibody, cleared minimal residual disease and protected against recurrence in patients with DNA mismatch repair-deficient (dMMR) early-stage solid cancers who had detectable circulati  more

AI-driven Biomarker Model May Improve Detection of Cancer Cachexia
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * AI-driven Biomarker Model May Improve Detection of Cancer Cachexia CHICAGO - A multimodal, artificial intelligence (AI)-driven model that analyzes routinely collected imaging and clinical information led to more accurate prediction of cancer cachexia than standard methods, according to results presented at the American Association for Cancer Researc  more

Five Nittany Lions taken in 2025 NFL Draft
UNIVERSITY PARK, Pennsylvania, April 27 -- Pennsylvania State University posted the following news: * * * Five Nittany Lions taken in 2025 NFL Draft GREEN BAY, Wisc. -- Five Penn State football players were selected during the 2025 NFL Draft, held April 24-26 in Green Bay, Wisconsin. In addition, several other Nittany Lions were signed as unrestricted free agents following the draft. Players drafted included: * Abdul Carter, defensive end -- New York Giants (1st round, 3rd pick) * Tyl  more

Neoadjuvant PD-1 Blockade in Early-stage Mismatch Repair-deficient Cancers Can Eliminate the Need for Surgery Regardless of Tumor Type
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * Neoadjuvant PD-1 Blockade in Early-stage Mismatch Repair-deficient Cancers Can Eliminate the Need for Surgery Regardless of Tumor Type CHICAGO - PD-1 blockade with dostarlimab (Jemperli) induced complete tumor clearance and resolved the need for surgery in patients with locally advanced, mismatch repair-deficient (dMMR) cancers, according to prelimi  more

Off-the-shelf CAR Natural Killer Cell Therapy with Logic Gates Elicits Complete Remissions in Relapsed or Refractory Blood Cancers
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * Off-the-shelf CAR Natural Killer Cell Therapy with Logic Gates Elicits Complete Remissions in Relapsed or Refractory Blood Cancers CHICAGO - Several patients with acute myeloid leukemia (AML), who were treated with SENTI-202, a first-in-class chimeric antigen receptor natural killer (CAR NK) cell therapy, experienced a complete remission after not r  more

Oral Investigational Agent Zoldonrasib Elicits Objective Responses in Patients With KRAS G12D-mutated Lung Cancer
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * Oral Investigational Agent Zoldonrasib Elicits Objective Responses in Patients With KRAS G12D-mutated Lung Cancer CHICAGO - Patients with previously treated non-small cell lung cancer (NSCLC) whose tumors harbored a KRAS G12D mutation experienced clinical benefit from the oral KRAS G12D inhibitor zoldonrasib, according to results presented at the Am  more

Pretrained Machine Learning Models May Help Accurately Diagnose Nonmelanoma Skin Cancer in Resource-limited Settings
PHILADELPHIA, Pennsylvania, April 27 [Category: Medical] -- The American Association for Cancer Research posted the following news release: * * * Pretrained Machine Learning Models May Help Accurately Diagnose Nonmelanoma Skin Cancer in Resource-limited Settings CHICAGO - Artificial intelligence models, pretrained on vast datasets, significantly outperformed a standard baseline model in identifying nonmelanoma skin cancers (NMSC) from digital images of tissue samples, according to research pr  more