Vanderbilt University Medical Center: Cellular Antiviral Defenses
July 24, 2020
July 24, 2020
NASHVILLE, Tennessee, July 24 -- Vanderbilt University Medical Center issued the following news:
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that regulates levels of both aberrant and wild-type cellular RNAs. It also contributes to antiviral immunity against select plant and human RNA viruses. However, whether NMD exerts an antiviral effect against DNA viruses was not known.
Now, John Karijolich, PhD, and colleagues have demonstrated that NMD restr . . .
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that regulates levels of both aberrant and wild-type cellular RNAs. It also contributes to antiviral immunity against select plant and human RNA viruses. However, whether NMD exerts an antiviral effect against DNA viruses was not known.
Now, John Karijolich, PhD, and colleagues have demonstrated that NMD restr . . .