Vanderbilt University Medical Center: Probing Innate Immunity
May 20, 2020
May 20, 2020
NASHVILLE, Tennessee, May 20 -- Vanderbilt University Medical Center issued the following news:
The protein cGAS plays an essential role in cellular innate immunity by detecting the DNA of invading pathogens such as bacteria and viruses, or our own damaged and mislocalized DNA. Activation of the cGAS-STING signaling pathway produces a pro-inflammatory immune response, and prolonged activation of cGAS can result in lupus-like autoimmune disorders.
Manuel Ascano, PhD, an . . .
The protein cGAS plays an essential role in cellular innate immunity by detecting the DNA of invading pathogens such as bacteria and viruses, or our own damaged and mislocalized DNA. Activation of the cGAS-STING signaling pathway produces a pro-inflammatory immune response, and prolonged activation of cGAS can result in lupus-like autoimmune disorders.
Manuel Ascano, PhD, an . . .