Vanderbilt University: One-Two Punch for Cancer
March 06, 2020
March 06, 2020
NASHVILLE, Tennessee, March 6 [TNSmedicalresearch] -- Vanderbilt University issued the following news:
Many cancer cells evade critical DNA surveillance and maintenance by increasing the export -- by the Exportin-1 (XPO1) nucleo-cytoplasmic transport protein -- of nearly all major tumor suppressor proteins from the nucleus. Thus, overexpression of XPO1 is often an indicator of poor prognosis in numerous malignancies.
Evasion of apoptosis, programmed cell death, is anoth . . .
Many cancer cells evade critical DNA surveillance and maintenance by increasing the export -- by the Exportin-1 (XPO1) nucleo-cytoplasmic transport protein -- of nearly all major tumor suppressor proteins from the nucleus. Thus, overexpression of XPO1 is often an indicator of poor prognosis in numerous malignancies.
Evasion of apoptosis, programmed cell death, is anoth . . .